Antidepressants Rarely Outperform Sugar Pills

Other Helpful Treatment Strategies

Additional strategies that can help improve your mental health include the following:⁴³

Minimize electromagnetic field (EMF) exposure — In 2016, Martin Pall, Ph.D., published a review⁴⁴ in the Journal of Neuroanatomy showing how microwave radiation from cellphones, Wi-Fi routers and computers and tablets not in airplane mode is clearly associated with many neuropsychiatric disorders.

These electromagnetic fields (EMFs) increase intracellular calcium and trigger the production of extremely damaging free radicals by acting on your voltage gated calcium channels (VGCCs), and the tissue with the highest density of VGCCs is your brain. Once these VGCCs are stimulated they also cause the release of neurotransmitters and neuroendocrine hormones, which contribute to anxiety and depression.

So, be sure to limit your exposure to wireless technology. Simple measures include turning your Wi-Fi off at night, not carrying your cellphone on your body unless it’s in airplane mode, and not keeping portable phones, cellphones and other electric devices in your bedroom.

Clean up your sleep hygiene — Make sure you’re getting enough high quality sleep, as sleep is essential for optimal mood and mental health. The inability to fall asleep and stay asleep can be due to elevated cortisol levels, so if you have trouble sleeping, you may want to get your saliva cortisol level tested with an Adrenal Stress Index test.

Adaptogens, herbal products that help lower cortisol and adjust your body to stress, can be helpful if your cortisol is running high. There are also other excellent herbs and amino acids that help you to fall asleep and stay asleep. For more tips and guidelines, see “Sleep — Why You Need It and 50 Ways to Improve It.”

Optimize your gut health — A number of studies have confirmed gastrointestinal inflammation can play a critical role in the development of depression.⁴⁵ Optimizing your gut microbiome will also help regulate a number of neurotransmitters and mood-related hormones, including GABA and corticosterone, resulting in reduced anxiety and depression-related behavior.⁴⁶

To nourish your gut microbiome, be sure to eat plenty of fresh vegetables and traditionally fermented foods such as fermented vegetables, lassi, kefir and natto. If you do not eat fermented foods on a regular basis, taking a high-quality probiotic supplement is recommended. Also remember to severely limit sugars and grains, to rebalance your gut flora.

Cognitive behavioral therapy (CBT) — CBT has been used successfully to treat depression.^47,48 This therapy assumes mood is related to the pattern of thought. CBT attempts to change mood and reverse depression by directing your thought patterns.

Make sure your cholesterol levels aren’t too low for optimal mental health — You may also want to check your cholesterol to make sure it’s not too low. Low cholesterol is linked to dramatically increased rates of suicide, as well as aggression toward others.⁴⁹

This increased expression of violence toward self and others may be due to the fact that low membrane cholesterol decreases the number of serotonin receptors in the brain, which are approximately 30% cholesterol by weight.

Lower serum cholesterol concentrations therefore may contribute to decreasing brain serotonin, which not only contributes to suicidal-associated depression, but prevents the suppression of aggressive behavior and violence toward self and others.

Ecotherapy — Studies have confirmed the therapeutic effects of spending time in nature. Ecotherapy has been shown to lower stress, improve mood and significantly reduce symptoms of depression.⁵⁰ Outdoor activities could be just about anything, from walking a nature trail to gardening, or simply taking your exercise outdoors.

Breathing exercises — Breath work also has enormous psychological benefits and can quickly reduce anxiety by increasing the partial pressure of carbon dioxide in your body. To learn more, see “Top Breathing Techniques for Better Health.”

Helpful supplements — A number of herbs and supplements can also be used in lieu of drugs to reduce symptoms of anxiety and depression, such as:

• St. John’s Wort (Hypericum perforatum) — This medicinal plant has a long historical use for depression, and is thought to work similarly to antidepressants, raising brain chemicals associated with mood such as serotonin, dopamine and noradrenaline.⁵¹
• S-Adenosyl methionine (SAMe) — SAMe is an amino acid derivative that occurs naturally in all cells. It plays a role in many biological reactions by transferring its methyl group to DNA, proteins, phospholipids and biogenic amines. Several scientific studies indicate that SAMe may be useful in the treatment of depression.
• 5-Hydroxytryptophan (5-HTP) — 5-HTP is another natural alternative to traditional antidepressants. When your body sets about manufacturing serotonin, it first makes 5-HTP. Taking 5-HTP as a supplement may raise serotonin levels. Evidence suggests 5-HTP outperforms a placebo when it comes to alleviating depression,⁵² which is more than can be said about antidepressants.
• XingPiJieYu — This Chinese herb, available from doctors of traditional Chinese medicine, has been found to reduce the effects of “chronic and unpredictable stress,” thereby lowering your risk of depression.⁵³

Guidelines for Safe Drug Withdrawal

If you’re currently on an antidepressant and want to get off it, ideally, you’ll want to have the cooperation of your prescribing physician. It would also be wise to do some homework on how to best proceed.

Dr. Peter Breggin’s book, “Psychiatric Drug Withdrawal: A Guide for Prescribers, Therapists, Patients and Their Families,”⁵⁴ and/or “The Antidepressant Solution: A Step-by-Step Guide to Overcoming Antidepressant Withdrawal, Dependence, and Addiction”⁵⁵ by Dr. Joseph Glenmullen can be helpful.

You can also turn to an organization with a referral list of doctors who practice more biologically or naturally, such as the American College for Advancement in Medicine at www.ACAM.org. A holistic psychiatrist will have a number of treatment options in their tool box that conventional doctors do not, and will typically be familiar with nutritional supplementation.

Once you have the cooperation of your prescribing physician, start lowering the dosage of the medication you’re taking. There are protocols for gradually reducing the dose that your doctor should be well aware of. At the same time, it may be wise to add in a multivitamin and/or other nutritional supplements or herbs. Again, your best bet would be to work with a holistic psychiatrist who is well-versed in the use of nutritional support.

If you have a friend or family member who struggles with depression, perhaps one of the most helpful things you can do is to help guide them toward healthier eating and lifestyle habits, as making changes can be particularly difficult when you’re feeling blue — or worse, suicidal.

Encourage them to unplug and meet you outside for walks. We should not underestimate the power of human connection, and the power of connection with nature. Both, I believe, are essential for mental health and emotional stability.

If you are feeling desperate or have any thoughts of suicide and reside in the U.S., please call the National Suicide Prevention Lifeline by dialing 988, or call 911, or simply go to your nearest hospital emergency department.

You cannot make long-term plans for lifestyle changes when you are in the middle of a crisis. U.K. and Irish helpline numbers can be found on TherapyRoute.com. For other countries, do an online search for “suicide hotline” and the name of your country.

Sources and References

• ¹ CDC NCHS Data Brief No. 377, September 2020
• ^{2, 3, 5, 6, 7, 12, 14, 15, 16} Newsweek September 21, 2022
• ⁴ Molecular Psychiatry July 20, 2022
• ⁸ BMJ 2022; 378: e067606
• ⁹ Dialogues in Clinical Neuroscience March 2002; 4(1): 105-113
• ^10, 11 Neuropsychiatric Disease Treatment 2013; 9: 915-920
• ¹³ PLOS ONE April 20, 2022
• ¹⁷ Mayo Clinic, Monoamine Oxidase Inhibitors
• ¹⁸ Drugs.com, Zoloft Side Effects
• ¹⁹ PLOS One July 31, 2017
• ²⁰ Diabetologia. 2012 Jan;55(1):63-72
• ²¹ Emory April 4, 2011
• ²² Indian J Pharmacol. 2015 May-Jun;47(3):256-62
• ²³ J Clin Psychiatry. 2016 Jan;77(1):117-22; quiz 122
• ²⁴ Wellness Resources October 9, 2017
• ²⁵ Journal of Alternative and Complementary Medicine March 1, 2017; 23(3)
• ²⁶ Scientific Reports July 27, 2017; 7, Article Number: 6287
• ²⁷ Translational Psychiatry (2016) 6, e756
• ²⁸ Psychother Psychosom. 2004 Nov-Dec;73(6):334-9
• ²⁹ Nutritionfacts.org March 30, 2017
• ³⁰ American Journal of Psychiatry January 1, 2017; 174(1): 42-50
• ³¹ Vice August 9, 2017
• ³² PLOS One June 27, 2017
• ³³ The Journal of Nutrition, Health & Aging 1999, 3(1):5-7
• ^34, 36 Journal of Internal Medicine 264(6); 599-609
• ^35, 37 Michigan State University October 7, 2014
• ³⁸ JAMA Psychiatry November 18, 2015. doi:10.1001/jamapsychiatry.2015.2235
• ³⁹ Traumatology September 1, 2012; 18(3)
• ⁴⁰ Depression Research & Treatment, 2012. doi:10.1155/2012/257172
• ⁴¹ Veteran Stress Project, EFT
• ⁴² Lissa Rankin April 15, 2013
• ⁴³ Care2 March 11, 2017
• ⁴⁴ Journal of Chemical Neuroanatomy September 2016; 75 Part B: 43-51
• ^45, 47 Nat Rev Immunol. 2016 Jan; 16(1): 22–34
• ⁴⁶ Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):16050-5
• ⁴⁸ Journal of Human Behavior in the Social Environment 2012; 22:463
• ⁴⁹ Eur Psychiatry. 2003 Feb ;18(1):23-7
• ⁵⁰ Depressionalliance.org, Ecotherapy
• ⁵¹ Nutrition. 2014 Jul-Aug; 30(0 0): S37–S42
• ⁵² Orvosi Hetilap 2011 Sep 11;152(37):1477-85
• ⁵³ BMC Complement Altern Med. 2017; 17: 73
• ⁵⁴ Psychiatric Drug Withdrawal: A Guide for Prescribers, Therapists, Patients and Their Families by Peter R. Breggin MD
• ⁵⁵ The Antidepressant Solution: A Step-by-Step Guide to Overcoming Antidepressant Withdrawal, Dependence, and Addiction by Joseph Glenmullen

The post Antidepressants Rarely Outperform Sugar Pills appeared first on LewRockwell.